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	Journal of Computer Science and Technology
	2010 Vol.25 No.1
	Published 2010-01-05

	Special Issue on Computational Challenges from Modern Molecular Biology

Special Issue on Computational Challenges from Modern Molecular Biology

	3	David C. Schwartz and Michael S. Waterman
		New Generations: Sequencing Machines and Their Computational Challenges
		2010 Vol. 25 (1): 3-9 [Chinese] [Abstract] ( 1697 ) [PDF 212KB] ( 1254 )

	10	David Sankoff, Chunfang Zheng, Adriana Muñoz, Zhenyu Yang, Zaky Adam, Robert Warren, Vicky Choi, and Qian Zhu
		Issues in the Reconstruction of Gene Order Evolution
		2010 Vol. 25 (1): 10-25 [Chinese] [Abstract] ( 1642 ) [PDF 661KB] ( 864 )

	26	Michael Q. Zhang and Andrew D. Smith, Member, ACM
		Challenges in Understanding Genome-Wide DNA Methylation
		2010 Vol. 25 (1): 26-34 [Chinese] [Abstract] ( 1537 ) [PDF 286KB] ( 1094 )

	35	Shoudan Liang
		Genome-Wide Analysis of Epigenetic Modifications
		2010 Vol. 25 (1): 35-41 [Chinese] [Abstract] ( 1673 ) [PDF 147KB] ( 894 )

	42	Tao Jiang, Fellow, ACM
		Some Algorithmic Challenges in Genome-Wide Ortholog Assignment
		2010 Vol. 25 (1): 42-52 [Chinese] [Abstract] ( 1373 ) [PDF 355KB] ( 713 )

	53	Ying Xu
		Computational Challenges in Deciphering Genomic Structures of Bacteria
		2010 Vol. 25 (1): 53-70 [Chinese] [Abstract] ( 1686 ) [PDF 648KB] ( 924 )

	71	John C. Wooley and Yuzhen Ye
		Metagenomics: Facts and Artifacts, and Computational Challenges
		2010 Vol. 25 (1): 71-81 [Chinese] [Abstract] ( 1684 ) [PDF 227KB] ( 1335 )

	82	Gloria Rendon, Mao-Feng Ger, Ruth Kantorovitz, Shreedhar Natarajan, Jeffrey Tilson, and Eric Jakobsson, Fellow, APS
		Understanding the "Horizontal Dimension'' of Molecular Evolution to Annotate, Classify, and Discover Proteins with Functional Domains
		2010 Vol. 25 (1): 82-94 [Chinese] [Abstract] ( 1762 ) [PDF 319KB] ( 789 )

	95	Ming Li, Fellow, ACM, IEEE, Royal Society of Canada
		Can We Determine a Protein Structure Quickly?
		2010 Vol. 25 (1): 95-106 [Chinese] [Abstract] ( 1438 ) [PDF 404KB] ( 836 )

	107	Bin Ma
		Challenges in Computational Analysis of Mass Spectrometry Data for Proteomics
		2010 Vol. 25 (1): 107-123 [Chinese] [Abstract] ( 1648 ) [PDF 386KB] ( 1024 )

	124	Limsoon Wong and Guimei Liu
		Protein Interactome Analysis for Countering Pathogen Drug Resistance
		2010 Vol. 25 (1): 124-130 [Chinese] [Abstract] ( 1543 ) [PDF 304KB] ( 786 )

	131	Rui Yamaguchi, Seiya Imoto, and Satoru Miyano
		Network-Based Predictions and Simulations by Biological State Space Models: Search for Drug Mode of Action
		2010 Vol. 25 (1): 131-153 [Chinese] [Abstract] ( 1426 ) [PDF 1174KB] ( 883 )

	154	Jie Liang and Hong Qian
		Computational Cellular Dynamics Based on the Chemical Master Equation: A Challenge for Understanding Complexity
		2010 Vol. 25 (1): 154-168 [Chinese] [Abstract] ( 1503 ) [PDF 512KB] ( 794 )

	169	Hong-Jie Dai, Yen-Ching Chang, Richard Tzong-Han Tsai, and Wen-Lian Hsu, Fellow, IEEE
		New Challenges for Biological Text-Mining in the Next Decade
		2010 Vol. 25 (1): 169-inside back cover [Chinese] [Abstract] ( 1655 ) [PDF 367KB] ( 961 )

Journal of Computer Science and Technology

   ISSN 1000-9000
   CN 11-2296/TP
   CODEN JCTEEM

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