Abstract: Recent advances in connected vehicles and autonomous driving are going to change the face of ground transportation as we know it. This paper describes the design and evaluation of several emerging applications for such a Cyber Transportation System (CTS). These applications have been designed using holistic approaches, which consider the unique roles played by the human drivers, the transportation system, and the communication network. They can improve driver safety and provide on-road infotainment. They can also improve transportation operations and efficiency, thereby benefiting travelers and attracting investment from both government agencies and private businesses to deploy infrastructures and bootstrap the evolutionary process of CTS.